CORRELATION OF THE PROGNOSTIC INDICATORS OF A BRAIN INJURY AT THE BIRTH AND THE OUTCOME OF THE NEWBORNS

Marija Novaković Bošnjak; Nina Knezović; Anita Kolobarić; Marjana Jerković Raguž

CORRELATION OF THE PROGNOSTIC INDICATORS OF A BRAIN INJURY AT THE BIRTH AND THE OUTCOME OF THE NEWBORNS

Authors

Marija Novaković Bošnjak Clinic for Children’s Diseases, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina https://orcid.org/0009-0003-0469-2497
Nina Knezović Clinic for Children’s Diseases, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina
Anita Kolobarić School of Medicine University of Mostar, Mostar, Bosnia and Herzegovina https://orcid.org/0000-0002-1361-8665
Marjana Jerković Raguž Clinic for Children’s Diseases, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina https://orcid.org/0000-0002-1158-7965

Keywords:

hypoxic-ischemic encephalopathy, lactic acid, metabolic acidosis, acid-base imbalance

Abstract

Background: To investigate the impact of blood acid-base disorders and elevated lactate during birth on the final outcome of the newborn.
Subjects and methods: The study include 110 children born with acid-base imbalance and increased level of lactates at the admission. We also took into account the assessment of the vitality of newborns at birth, need for resuscitation procedures and mechanical ventilation, ultrasound scanning of the brain, treatment methods and final outcome.
Results: Research has shown that 80% of the newborns had the disorder of acid-base status of blood on admission and 76.3% had high lactates. On admission, 53.60% of the newborns had clinical features of hypoxic ischemic encephalopathy. Ultrasound scanning images of brain have been pathologically changed in 92.70% and mechanical ventilation was necessary at 90.90% of the newborns.
Conclusion: After completed treatment, all examinees have survived. These indicators of hypoxic ischemic injury at our patients had no significant impact on the treatment outcome.

CORRELATION OF THE PROGNOSTIC INDICATORS OF A BRAIN INJURY AT THE BIRTH AND THE OUTCOME OF THE NEWBORNS