CREATIVE PSYCHOPHARMACOTHERAPY OF PSYCHOGENIC NON–EPILEPTIC SEIZURES

CREATIVE PSYCHOPHARMACOTHERAPY OF PSYCHOGENIC NON–EPILEPTIC SEIZURES

Authors

  • Biljana Dapic Ivancic Department of Neurology, University Hospital Centre Zagreb and School of Medicine, University of Zagreb, Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy, Affiliated Partner of the ERN EpiCARE https://orcid.org/0000-0001-6566-501X
  • Zeljka Petelin Gadze Department of Neurology, University Hospital Centre Zagreb and School of Medicine, University of Zagreb, Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy, Affiliated Partner of the ERN EpiCARE https://orcid.org/0000-0003-0471-5479
  • Katarina Popadic Department of Neurology, University Hospital Centre Zagreb and School of Medicine, University of Zagreb, Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy, Affiliated Partner of the ERN EpiCARE
  • Maja Zivkovic Department of Psychiatry and Psychological medicine, University Hospital Centre Zagreb and School of Medicine, University of Zagreb, Croatia https://orcid.org/0000-0002-1188-0723

Keywords:

psychogenic non-epileptic seizures, epilepsy, psychotropic medications, psychotherapeutic modalities

Abstract

Background: Aim of this review was to evaluate management of PNES from neurological and psychiatric perspective.
Results: Management of PNES is interdisciplinary. The first treatment phase in PNES should be engaging patients into treatment, which is often challenging. There are several psychopathological dimensions particularly important vulnerable to develop PNES including endogenous anxiety, avoidance behaviour, dissociation, non-dissociative post-traumatic stress, abuse, interpersonal dynamics, personality structure and society and family factors. Early correct diagnosis can help patients promptly receive the treatment they need and prevent common iatrogenic complications that may occur if the condition continues to be misdiagnosed and mistreated.
Conclusion: Although evidence is mixed for the treatment of PNES, psychotherapeutic modalities remain a powerful instrument to help patients and reduce seizures. A multidisciplinary, holistic approach is significant. It is important to aim to improve quality with specific treatment. For patients refractory to all possible treatments further investigation should be performed.

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Published

11.12.2025

How to Cite

Dapic Ivancic, B., Petelin Gadze, Z., Popadic, K., & Zivkovic, M. (2025). CREATIVE PSYCHOPHARMACOTHERAPY OF PSYCHOGENIC NON–EPILEPTIC SEIZURES. Medicina Academica Integrativa, 2(1-2), 15–18. Retrieved from https://pauk.sum.ba/ojs/mai/article/view/436

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